Possible Interaction: Calcium Supplement and Ferric Ion

“The determination of several parameters (iron, calcium, magnesium, alpha-hydroxyproline, lipid peroxidation, hepatomegalic and splenomegalic indexes) showed that ferrous and ferric lactates provoke an increase of calcium in the liver, higher than that of ethanol in the control animals.”

“ Calcium significantly diminishes the absorption of ferrous and ferric iron in a dose-related manner, whether the test doses of calcium and radioiron are administered orally or introduced into isolated intestinal segments; the effect is maximal in the duodenum and jejunum.”

“The higher Fe(III) reduction rates and lower Fe(II) oxidation rates in the presence compared to the absence of calcium will help to maintain higher concentrations of Fe(II) thereby increasing the bioavailability of iron in calcium-containing waters.”

“While the exact mechanism via which the Fe(III) reduction rate under irradiated conditions is impacted by calcium addition is not clear, the formation of more photolabile weakly complexed Fe(III)SRFA is most consistent with our experimental results.”

“The presence of Cu ++ , Zn ++ , Fe +++ , and Fe ++ ions resulted in low titration values for calcium.”

“Suppression of pesticin I activity by Fe+++ can be reversed by the addition of either Ca++ or Sr++ or by metal chelating agents.”