Allen Institute for Artificial Intelligence logo

Discover Supplement-Drug Interactions

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 3 months ago

Possible Interaction: Calcium Phosphate and Silicon



Research Papers that Mention the Interaction

The results show that simultaneous incorporation of strontium and silicon into calcium phosphate cements changes properties of the cement such as solubility, and nearly abrogates the inhibitory effects of strontium on osteoclastogenesis.
Biomedical materials  •  2019  |  View Paper
Silicon and strontium are both present in trace concentrations in natural bone and have been demonstrated, by separate, to significantly improve osteoblastic response on calcium phosphate bioceramics.
Journal of biomaterials applications  •  2014  |  View Paper
It was found that an appropriate addition of silicon in nanocalcium phosphate scaffolds leads to an enhanced adhesion and proliferation of cells in osteoblasts in vitro.
Materials science & engineering. C, Materials for biological applications  •  2014  |  View Paper
Silicon is known to have an influence on calcium phosphate deposition and on the differentiation of bone precursor cells.
Acta biomaterialia  •  2012  |  View Paper
Furthermore, adding silicon may increase the bioactivity of calcium phosphate and enhance interactions at the graft-host interface.
American journal of orthopedics  •  2008  |  View Paper
The resulting calcium phosphate is modified by the incorporation of silicon into its structure with excess silica contributing to an amorphous component.
Biomaterials  •  2003  |  View Paper
Si , an essential trace element required for healthy bone and connective tissues, influences the biological activity of CaP materials by modifying material properties and by direct effects on the physiological processes in skeletal tissue.
Biomaterials  •  2007  |  View Paper