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Discover Supplement-Drug Interactions

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Last Updated: 2 months ago

Possible Interaction: Calcium Pantothenate and Salicylic Acid

Research Papers that Mention the Interaction

Although several workers have observed that the bacteriostatic effect of salicylate can be reversed by pantothenate , there is disagreement about the reaction step affected.
Salicylate has been considered to inhibit synthesis of pantoate (Ivanovics, 1942), the conversion of pantoate to pantothenate (Roblin, 1949), and the utilization of pantothenate (Mcllwain, 1943; Work and Work, 1948); Ackeimann and Shive (1948) remained undecided between synthesis and utilization of pantoate.
Journal of bacteriology  •  1952  |  View Paper
In low concentrations, salicylic acid is thought to inhibit growth of bacteria which synthesize pantothenate (e.g., Escherichia coli) by preventing the formation of pantoic acid or pantolactone (2).
The Journal of biological chemistry  •  1945  |  View Paper