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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Calcium Glucarate
drug:
Isotretinoin
Research Papers that Mention the Interaction
“ Dietary calcium glucarate (CGT) increased the activity of non-toxic levels of dietary isotretinoin against pre-established tumors in the chemically-induced rat mammary tumour model.”
“In contrast, the combination of 1.0 mmol/kg of isotretinoin and 64 mmol/kg of CGT caused a reversible inhibition of tumour growth, culminating in a net decrease in tumour volume of 20%.”
Antitumour synergism between non-toxic dietary combinations of isotretinoin and glucarate.“Furthermore, ineffective sub-optimal dosages of glucarate and 13-cis-retinoic acid interacted synergistically to inhibit the growth in vitro of the MCF-7 human breast cancer cells.”
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