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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Calcium Chloride
drug:
Verapamil
Research Papers that Mention the Interaction
“We report a case of a 61-…-old woman treated for a suspected verapamil overdose … continuous calcium chloride infusion, resulting in severe hypercalcemia of 32.3 mg/dL (8.07 mmol/L) with a normal range of 8.6–10.5 mg/dL (2.15–2.63 mmol/L).”
A fatal case of iatrogenic hypercalcemia after calcium channel blocker overdose“We report the case of a patient with SVT and a systolic blood pressure of 80 mm Hg in which the administration of calcium chloride prior to that of verapamil may have negated verapamil-induced hypotension.”
“It is suggested from this study that, although calcium chloride counteracts the negative inotropic effects of verapamil and diltiazem, abruptly increased ionized calcium may cause severe bradycardia clinically.”
Effects of calcium chloride on verapamil- and diltiazem-pretreated isolated rat hearts.“On the other hand, verapamil (2.04 mmol.l-1), a calcium channel blocker, also produces a complete neuromuscular blockade at the above preparation which is reversed by calcium chloride.”
“ Calcium chloride reversed the impairment of global and regional myocardial function observed with verapamil , improved the impaired left ventricular relaxation, but did not significantly alter atrioventricular conduction.”
“ calcium chloride reverses this regional myocardial dysfunction as well as the deleterious global haemodynamic changes caused by halothane‐verapamil ; however, the changes in atrioventricular conduction are not corrected by calcium.”
“The fact that the effects of Tet and Ver on the heart performance are very similar and can all be reversed by calcium chloride gives further support to the speculation that Tet might be a slow channel blocker.”
“ Calcium chloride reverted the inhibitory effect of verapamil and LAs.”
Interaction of local anaesthetics with other antifungal agents against pathogenic Aspergillus.
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