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Archives of pathology & laboratory medicine • 1994 | View Paper
“Ionized hypocalcemia due to the chelating effect of sodium citrate was controlled by calcium chloride administration , adjustment of blood separation rates, and reduction of the blood‐to‐citrate ratio.”
“Since calcium chloride was found to offset the inhibitory effect of sodium citrate , it was assumed that the sex-related differences observed in platelet activity were due to varied levels of ionized calcium.”
“Bunker and associates 7 were able to reverse the effects of sodium citrate by the intravenous administration of calcium chloride , but they found that the increase in ionized calcium in the blood could not be predicted on the basis of the amount of calcium administered.”
“The inhibitory effects of sodium citrate were reversed by calcium chloride while the action of triethyl citrate underwent little or no change under similar conditions.”