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Last Updated: a year ago

Possible Interaction: Calcium Channel Blockers and Potassium

Research Papers that Mention the Interaction

In direct comparison with ACEIs or ARBs (11 trials), CCBs increased GFR [MD 11.07 mL/min (95% CI 6.04-16.09)] and reduced potassium levels but were not more effective in reducing BP.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association  •  2019  |  View Paper
ECGs from 145 patients receiving a combined potassium and sodium channel blocking agent for conversion of atrial fibrillation (AF), underwent semiautomatic analysis in a digitalized high-precision analysis program.
Scandinavian cardiovascular journal : SCJ  •  2010  |  View Paper
Antiarrhythmic drugs class IA (quinidine, disopyramide), … (sotalol, amiodarone), class IV calcium channel blockers ) used at the … time with potassium depleters diuretics or beta-blocking agents result in the inhibition of repolarization and the increased duration … activation potential with the risk of developing arrhythmia of the torsade de pointes types.
Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego  •  2000  |  View Paper
The calcium channel antagonists , nifedipine, verapamil and diltiazem (0.01-10 microM), inhibited responses to high potassium , and the initial phase of shortening and lengthening responses to noradrenaline.
Journal of autonomic pharmacology  •  1993  |  View Paper
Potassium chloride-induced contractions were completely inhibited by the calcium channel blockers diltiazem and nifedipine or by excluding Ca2+ from the medium.
The Journal of the American Osteopathic Association  •  1992  |  View Paper
Minor lowering of plasma potassium levels during a CA regimen was exceptional and a rise of plasma uric acid values never reported; the latter may even decrease under certain circumstances.
Journal of cardiovascular pharmacology  •  1988  |  View Paper
Contractions which were triggered by action potentials or depolarizing extracellular potassium concentrations were highly sensitive to calcium channel blockers.
Der Urologe. Ausg. A  •  1986  |  View Paper
In pial arteries the calcium antagonists nifedipine and nimodipine caused an almost complete relaxation of contractions induced by potassium at drug concentrations relaxing prostaglandin F2α-contracted vessels to only about 60%.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism  •  1981  |  View Paper
A combined use of potassium and calcium antagonists may reduce the frequency-dependence of the pure class III antiarrhythmic drug.
Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition  •  2009  |  View Paper
The types of calcium channels present at the synaptic terminal were determined by the inhibitory action of calcium channel blockers on potassium‐induced [3H]GABA release in the same cell preparation.
International Journal of Developmental Neuroscience  •  2001  |  View Paper
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