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Discover Supplement-Drug Interactions

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Last Updated: a year ago

Possible Interaction: Calcium Channel Blockers and Melatonin

Research Papers that Mention the Interaction

Inorganic (Co2+ and Cd2+) and organic (nifedipine and diltiazem) calcium channel blockers at 10(-4) mol/l all significantly reduced melatonin production and this inhibition was more effective with the glands removed 7 HALO.
Molecular and cellular endocrinology  •  1994  |  View Paper
The present results suggest that melatonin can inhibit bladder smooth muscle contraction through a voltage-dependent, calcium-antagonistic mechanism and through the inhibition of the calmodulin/CaMKII system.
The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology  •  2012  |  View Paper