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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Calcium Carbonate
drug:
Ranitidine
Research Papers that Mention the Interaction
“In patients on chronic hemodialysis their hyperphosphatemia is associated to gastric hypersecretion but the inhibition of this latter by ranitidine in patients taking CaCO3 has been reported to increase their plasma phosphate.”
[Inhibition of gastric secretion by omeprazole and efficacy of calcium carbonate in the control of hyperphosphatemia in patients on maintenance hemodialysis].“In chronic hemodialysis patients, gastric hypersecretion is associated with hyperphosphatemia, but inhibition of gastric hypersecretion by ranitidine in those receiving calcium carbonate (CaCO3) as a phosphate binder would paradoxically exacerbate their hyperphosphatemia.”
“CONCLUSION This study shows that ra itidine ha s a significant adverse effect on the phosphate binding of cal cium carbonate in patients with renal failure.”
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