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Last Updated: 3 years ago

Possible Interaction: Calcium Carbonate and Iron, Dietary

supplement:

Iron, Dietary

Research Papers that Mention the Interaction

Supplementing 500 mg Ca as calcium carbonate significantly (P = 0.0009) reduced Fe absorption from a single meal from 10.2 % (range 2.2-40.6) to 4.8 % (range 0.7-18.9).
The British journal of nutrition  •  2010  |  View Paper
Sodium bicarbonate and calcium carbonate caused the plasma iron increase to be 50% and 67% less than the control values, respectively.
JAMA  •  1986  |  View Paper
It is concluded that high intake of CaCO3 depresses Fe bioavailability in rats.
The British journal of nutrition  •  1996  |  View Paper
The results showed that CaCO3 application significantly increased the pH level, available P and exchangeable Ca but decreased organic matter, available Cd, exchangeable Cd, available heavy metals ( Fe , Mn, Zn and Cu) and available K in soil.
Journal of environmental biology  •  2016  |  View Paper
Further addition of CaCO3 resulted in immobilization of aqueous iron and sulfur due to elevated pH and gypsum formation.
Environmental Geochemistry and Health  •  2013  |  View Paper
In addition, less iron was taken up from digests with calcium carbonate relative to calcium acetate even though similar amounts of soluble iron were observed in these experiments.
The Journal of nutritional biochemistry  •  2000  |  View Paper