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Discover Supplement-Drug Interactions
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Last Updated: 2 years ago
supplement:
Calcium Ascorbate
supplement:
Vitamin C
Research Papers that Mention the Interaction
“However, at 24 hours, calcium ascorbate with metabolites resulted in significantly higher concentrations of vitamin C in leukocytes (P<0.0001) compared with vitamin C alone.”
Vitamin C metabolites, independent of smoking status, significantly enhance leukocyte, but not plasma ascorbate concentrations“ Calcium ascorbate has been developed to mitigate the gastric irritation caused by the acidity of ascorbic acid.”
“The area under the curve (AUC) values of calcium ascorbate were 1.5-fold higher than those of ascorbic acid , and the Cmax value of calcium ascorbate (91.0 ng/ml) was higher than that of ascorbic acid (74.8 ng/ml).”
“Thus, although calcium ascorbate showed equivalent antioxidant activity to ascorbic acid, it could attenuate the gastric high acidity caused by ascorbic acid , making it suitable for consideration of use to improve the side effects of ascorbic acid.”
Alleviation of ascorbic acid-induced gastric high acidity by calcium ascorbate in vitro and in vivo
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