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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Niacin
Research Papers that Mention the Interaction
“ Nicotinic acid mitigates pain, not only by its vasodilatory effects, but also through multiple mechanisms such as induction of PGD2 … the skin and subsequent increase of its metabolite in the plasma which might down-regulate the output of CGRP , and halt the neurogenic infl … and normalize the vascular tone.”
Nicotinic acid in erythromelalgia associated with Clitocybe acromelalga intoxication: Theories and therapy“The results suggest that calcitonin gene-related peptide and vasoactive intestinal peptide have inhibitory effects on the nicotinic action , and release of endogenous calcitonin gene-related peptide and/or vasoactive intestinal peptide may influence sweating in human skin under physiological conditions in vivo.”
“6 These findings indicate that CGRP potentiates the nicotinic ACh receptor‐operated slow Ca2+ signal via the activation of protein kinase‐A system at the skeletal muscle endplates.”
Calcitonin gene‐related peptide potentiates nicotinic acetylcholine receptor‐operated slow Ca2+ mobilization at mouse muscle endplates
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