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Last Updated: 3 years ago
supplement:
Capsaicin
Research Papers that Mention the Interaction
“ Capsaicin increased the release of iCGRP from dental pulp biopsies in a concentration‐dependent manner.”
Capsaicin-evoked iCGRP release from human dental pulp: A model system for the study of peripheral neuropeptide secretion in normal healthy tissue“Administration of capsaicin increases CGRP and IGF-I levels in plasma, kidneys and the heart in SHR to WKY levels, and normalizes mean arterial blood pressure in SHR.”
“In the GI tract of animals neuropeptides like tachykinins and calcitonin gene-related peptide (CGRP) mediate specific excitatory and inhibitory effects of capsaicin ; some evidence indicates a participation of purinergic mechanisms as well.”
“ Capsaicin activates vanilloid receptor-1, thereby increasing the release of calcitonin gene-related peptide (CGRP) from sensory neurons, and CGRP has been shown to increase IGF-I production.”
“ Capsaicin increases calcitonin gene-related peptide (CGRP) release from sensory neurons by stimulating vanilloid receptor-1 (VR-1).”
“Interestingly, there were significant increases in CGRP levels after exposure to vehicle (ethanol) as well as capsaicin , although this did not induce relaxant responses.”
“Release of neurotransmitters such as calcitonin gene-related peptide (CGRP) and the consequent increase in mucosal blood flow have been identified as key factors in the protective effect of the stimulation of these fibers by capsaicin.”
“AT significantly increased CGRP release from cultured dorsal root ganglion neurons isolated from rats in the presence of capsaicin.”
“ Capsaicin pretreatment resulted in lower myocardial levels of CGRP , and ischaemic myocardium had lower content of CGRP than non-ischaemic areas.”
“On the other hand, arterial infusion of capsaicin significantly increased the release of not only CGRP but also somatostatin from the stomach of normal rats.”
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