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Last Updated: 2 years ago

Possible Interaction: Caffeine and Theobromine

supplement:

Caffeine

Research Papers that Mention the Interaction

Considering animal studies, it … that acute exposition to theobromine has a reduced and … with respect to caffeine , whereas both animal and human studies suggested a potential neuroprotective action of long-term assumption of … a reduction of Aβ amyloid pathology, which is commonly observed in Alzheimer’s disease patients’ brains.
Psychopharmacology  •  2019  |  View Paper
Specific sets of constituent compounds such as polyphenols, theobromine and L‐theanine appear to enhance mood and cognition effects of caffeine and alleviate negative psychophysiological effects of caffeine.
Progress in Neuro-Psychopharmacology and Biological Psychiatry  •  2018  |  View Paper
The current American Society of Nuclear Cardiology (ASNC) imaging guidelines 5 recommend that caffeine and other methylxanthines (such as aminophylline or theobromine ) be withheld for at least 12 hours prior to vasodilator stress MPI and list this as a contraindication for performing the test.
Journal of Nuclear Cardiology  •  2012  |  View Paper
Guarana has been used for centuries as a stimulant in South America, due to its high caffeine content; it also contains xanthine alkaloids, such as theobromine and theophylline, which enhance the effects of caffeine.
British Journal of Sports Medicine  •  2011  |  View Paper
The combination of theobromine and caffeine , methylxanthines found in chocolate, has previously been shown to improve mood and cognition.
This study tested the hypothesis that a combination of caffeine and theobromine has synergistic effects on cognition, mood and blood pressure in 24 healthy female subjects.
Physiology & Behavior  •  2011  |  View Paper
Guarana, which contains caffeine in addition to small amounts of theobromine , theophylline, and tannins, is also recognized as safe by the FDA, although it may lead to caffeine toxicity when combined with caffeine.
The Physician and sportsmedicine  •  2010  |  View Paper
Caffeine interfered with the Vision, Seralyzer, and AccuLevel methods, and theobromine interfered with the Vision, Seralyzer, and TheoFAST methods.
Clinical chemistry  •  1990  |  View Paper
Both doses of theacrine could significantly prolong the sleeping time induced by pentobarbital, while caffeine and theobromine exhibited an inverted effect.
Journal of Asian natural products research  •  2007  |  View Paper
These results indicate that mixtures of theobromine and caffeine have the potential to be developed into a selective, effective, and socially acceptable toxicant for the control of pest coyotes.
Journal of agricultural and food chemistry  •  2005  |  View Paper
In the shuttle avoidance, up to 3 mg/kg of caffeine , and 10 and 30 mg/kg of theophylline or theobromine significantly increased the response rate, though there was no significant change in the avoidance rate at any doses of these methylxanthines.
The Journal of toxicological sciences  •  1993  |  View Paper
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