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“On the basis that TBZ augmented the secretory responses to caffeine (but not those of histamine), we monitored its effects on cytosolic Ca2+ elevations ([Ca2+]c) triggered by caffeine or histamine.”
“While the responses to caffeine were augmented twice by TBZ , those of histamine were unaffected; the same happened in rat cortical neurons.”
The Journal of Pharmacology and Experimental Therapeutics • 2019 | View Paper
“ Caffeine at doses that had no effect on their own reversed the effects of TBZ on T‐maze performance, and also suppressed TBZ‐induced pDARPP‐32(Thr34) expression as measured by western blot, suggesting a role for D2‐A2A interactions.”