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Last Updated: 3 years ago

Possible Interaction: Caffeine and Tetrabenazine

supplement:

Caffeine

Research Papers that Mention the Interaction

On the basis that TBZ augmented the secretory responses to caffeine (but not those of histamine), we monitored its effects on cytosolic Ca2+ elevations ([Ca2+]c) triggered by caffeine or histamine.
While the responses to caffeine were augmented twice by TBZ , those of histamine were unaffected; the same happened in rat cortical neurons.
The Journal of Pharmacology and Experimental Therapeutics  •  2019  |  View Paper
Caffeine at doses that had no effect on their own reversed the effects of TBZ on T‐maze performance, and also suppressed TBZ‐induced pDARPP‐32(Thr34) expression as measured by western blot, suggesting a role for D2‐A2A interactions.
Neuropharmacology  •  2018  |  View Paper