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Discover Supplement-Drug Interactions
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Last Updated: 5 years ago
Research Papers that Mention the Interaction
“Although the mechanisms by which the suppression of these pathways induces p53-mediated apoptotic cell death remain unclear, the combination of decaffeinated coffee, caffeine, and tamoxifen also caused cell-cycle arrest and apoptotic cell death, suggesting that unknown compound(s) present in decaffeinated coffee cooperate with caffeine and tamoxifen.”
Coffee decoction enhances tamoxifen proapoptotic activity on MCF-7 cells“Albain and colleagues have shown that addition of tamoxifen to cyclophosphamide, doxorubicin, and fl uorouracil ( CAF ) within the fi rst 6 months exerts a longlasting eff ect.”
“ Tamoxifen in combination with CMF or CAF can reduce plasma VEGF level in patients with estrogen receptor positive tumor but not in estrogen receptor negative tumor.”
“Ca2+ transients in isolated cardiac ventricular myocytes and the amount of Ca2+ that could be released from the sarcoplasmic reticulum (SR) in these cells by caffeine were reduced in the presence of tamoxifen.”
Tamoxifen inhibits Ca2+ uptake by the cardiac sarcoplasmic reticulum“When the anti-estrogen, tamoxifen , was added to CAF and CMF treatments, further declines in gp52 levels (below CAF and CMF levels) reflected the fact that these hormone-augmented treatments were more effective than either hormone or combination chemotherapy alone.”
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