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Last Updated: 2 months ago

Possible Interaction: Caffeine and Tamoxifen

supplement:

Caffeine

Research Papers that Mention the Interaction

Albain and colleagues have shown that addition of tamoxifen to cyclophosphamide, doxorubicin, and fl uorouracil ( CAF ) within the fi rst 6 months exerts a longlasting eff ect.
The Lancet  •  2010  |  View Paper
Tamoxifen in combination with CMF or CAF can reduce plasma VEGF level in patients with estrogen receptor positive tumor but not in estrogen receptor negative tumor.
International journal of oncology  •  2002  |  View Paper
Ca2+ transients in isolated cardiac ventricular myocytes and the amount of Ca2+ that could be released from the sarcoplasmic reticulum (SR) in these cells by caffeine were reduced in the presence of tamoxifen.
Pflügers Archiv  •  2000  |  View Paper
When the anti-estrogen, tamoxifen , was added to CAF and CMF treatments, further declines in gp52 levels (below CAF and CMF levels) reflected the fact that these hormone-augmented treatments were more effective than either hormone or combination chemotherapy alone.
Life sciences  •  1994  |  View Paper
Although the mechanisms by which the suppression of these pathways induces p53-mediated apoptotic cell death remain unclear, the combination of decaffeinated coffee, caffeine, and tamoxifen also caused cell-cycle arrest and apoptotic cell death, suggesting that unknown compound(s) present in decaffeinated coffee cooperate with caffeine and tamoxifen.
Scientific reports  •  2020  |  View Paper