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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Caffeine and Spermine



Research Papers that Mention the Interaction

Finally, pretreatment of the sea urchin egg homogenates with caffeine or Sr2+ and Ca2+ prevented the inhibitory effect of spermine on cADPR-induced Ca2+ release.
The American journal of physiology  •  1995  |  View Paper
Spermine (1 mM) inhibited transient contractions induced in Ca(2+)-free medium by carbachol (0.1 mM) and GTP gamma S (0.1 mM) but potentiated responses to caffeine (20 mM) and D-myo-inositol 1,4,5-trisphosphate (40 microM).
The American journal of physiology  •  1994  |  View Paper
Spermine caused even more striking antimutagenic effects when mutations were induced by the inclusion of caffeine in the culture medium4 or by ultra-violet light.
Nature  •  1965  |  View Paper