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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Caffeine
drug:
Sertraline
Research Papers that Mention the Interaction
“ Sertraline and mirtazapine enhanced the rates of all caffeine oxidation pathways.”
Caffeine metabolism during prolonged treatment of rats with antidepressant drugs.“ Sertraline decreased significantly the rate of 1-N- and 3-N-demethylation and 8-hydroxylation (Ki = 37.3, 69.3 and 64 microM, respectively), while its effect on 7-N-demethylation of caffeine was less pronounced (Ki = 92.1 microM).”
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