“Sertindole was a very poor inhibitor of 1-N- and 7-N-demethylations and 8-hydroxylation pathways ….1 and 173.3 microM, respectively); even the observed in vitro inhibition of 3-N-demethylation of caffeine … sertindole (Ki = 68.9 microM) cannot be of … and therapeutic doses of the neuroleptic.”