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Discover Supplement-Drug Interactions

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Last Updated: 6 months ago

Possible Interaction: Caffeine and Rolipram

supplement:

Caffeine

Research Papers that Mention the Interaction

The addition of caffeine and rolipram inhibited TGF-β1 induced reporter gene activity in a concentration-related manner.
PloS one  •  2014  |  View Paper
F‐stimulated cAMP accumulation (1 μM) in cortex slices was inhibited 98% by 1 mM CAF and 49% by 1 mM 3‐isobutyl‐1‐methylxanthine, and was enhanced 2.5‐fold by 100 μM rolipram.
Journal of neurochemistry  •  1992  |  View Paper
This effect was enhanced by the phosphodiesterase inhibitor rolipram , but blocked by alkylxanthines such as caffeine , theophylline and, particularly, 8-phenyl-theophylline.
Pharmacology Biochemistry and Behavior  •  1983  |  View Paper