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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Caffeine and Radiation-Sensitizing Agents

Research Papers that Mention the Interaction

Treatment (96 h) with 2 mM caffeine resulted in an abrogation of the cellular G2 checkpoint in both E6+ and control cells and a differential radiosensitizing effect on the two cell lines such that the E6+ clones and the vector controls became equally radiosensitive.
Cancer research  •  1995  |  View Paper
Caffeine inhibits ATM and ATR, two important checkpoint regulators, abolishes ionizing radiation-induced checkpoint response, and radiosensitizes cells.
Radiation research  •  2003  |  View Paper
This, together with the pharmacology of the release, suggests that caffeine increases intracellular calcium by sensitizing calcium‐induced calcium release.
The Journal of physiology  •  1992  |  View Paper