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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Caffeine
drug:
Pyrazinamide
Research Papers that Mention the Interaction
“This study investigated if, and in what manner, concomitant administration of caffeine affects PZA metabolism.”
“… kg−1 caffeine … PZA increased from the excretion (p<0.05) of the most water‐soluble and the least toxic PZA metabolite 5‐hydroxypyrazinoic acid (5‐OH‐… 173.23±17.82 μmol/24 h. These results show that the metabolic disposition of PZA is affected by concomitant caffeine intake.”
Investigation of the effects of concomitant caffeine administration on the metabolic disposition of pyrazinamide in rats
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