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Last Updated: 3 years ago

Possible Interaction: Caffeine and Psychotropic Drugs

Research Papers that Mention the Interaction

Smokers often consume more caffeine than non-smokers and the combined effects of these two psychoactive drugs result in an enhanced analgesic effect of nicotine.
Journal of psychoactive drugs  •  2016  |  View Paper
Together, our findings demonstrate that caffeine influences human circadian timing, showing one way that the world’s most widely consumed psychoactive drug affects human physiology.
Science Translational Medicine  •  2015  |  View Paper
It is postulated that deleterious effects may result from the interaction of caffeine with commonly prescribed psychotropic drugs.
Psychological reports  •  1996  |  View Paper
Thus, caffeine might interfere with the clearance of some psychotropic drugs which are mainly excreted by the kidneys, e.g., lithium.
Biological Psychiatry  •  1995  |  View Paper
PTDs can interfere also with the antiinflammatory effects of AIDs, since caffeine and guaifenesin, but not nomifensine, increased the antiinflammatory effects of aspirin and paracetamol, although neither caffeine nor nomifensine interfered with the effect of Auranofin.
International journal of tissue reactions  •  1985  |  View Paper
Certain psychotropic drugs when combined with caffeine significantly enhanced the antitumor effect of 1,3-bis(2-chloroethyl)-1-nitrosourea in murine leukemia L1210.
The Journal of pharmacology and experimental therapeutics  •  1975  |  View Paper
The results demonstrated that psychoactive drugs were adulterated with different drug categories, such as tramadol, ketamine, methadone, acetaminophen, and caffeine.
Journal of psychoactive drugs  •  2018  |  View Paper
Caffeine can inhibit the metabolism of some psychotropic drugs such as clozapine through the competitive inhibition of CYP 1A2 .
International journal of psychiatry in clinical practice  •  2001  |  View Paper