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Possible Interaction: Caffeine and Procaine

supplement:

Caffeine

supplement:

Procaine

Research Papers that Mention the Interaction

The cell vacuolisation cannot be prevented by 3-methyadenine, brefeldine A, and cytochalasine D. On the other hand, nocodazole and caffeine prevent cytoplasm vacuolisation induced by procaine.
European journal of pharmacology  •  2003  |  View Paper
The effect of caffeine was inhibited by intracellular injection of procaine or Ruthenium Red.
The Journal of experimental biology  •  1994  |  View Paper
Procaine (5 mM) antagonizes the effect of caffeine.
The Journal of General Physiology  •  2018  |  View Paper
RESULTS Caffeine induced a marked increase in intracellular Ca(2+) concentration which was then decreased 12% upon the addition of procaine (P < 0.05); however, lidocaine, did not induce a similar inhibitory reaction.
RESULTS Caffeine induced a marked increase in intracellular Ca(2+) concentration which was then decreased 12% upon the addition of procaine (P < 0.05); however, lidocaine, did not induce a similar inhibitory reaction.
Chinese medical journal  •  2002  |  View Paper
The response to 25 mM caffeine was only moderately inhibited by 25 mM procaine , and almost completely abolished by 50 mM procaine and 100 microM ryanodine.
Comparative biochemistry and physiology. Part A, Molecular & integrative physiology  •  2001  |  View Paper
(45)Ca(2+) release induced by caffeine was completely inhibited by typical blockers of Ca(2+)-induced Ca(2+) release, such as Mg(2+), ruthenium red, or procaine.
Molecular pharmacology  •  2000  |  View Paper
Procaine (1 mM) inhibited the transient contraction induced by caffeine (10 mM) in Ca2+-free Krebs solution.
European journal of pharmacology  •  1999  |  View Paper
Procaine , an antagonist of ryanodine receptor, selectively blocked the effect of caffeine but not the effect of InsP3.
Biochemical and biophysical research communications  •  1997  |  View Paper
On the other hand, procaine inhibited the responses to caffeine , but not those to IP3.
Yonsei medical journal  •  1996  |  View Paper
Surprisingly, procaine had only a minor effect on tension transients elicited by Cl− and caffeine together.
The Journal of Membrane Biology  •  1996  |  View Paper
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