Allen Institute for Artificial Intelligence
supp.ai logo
supp.ai

Discover Supplement-Drug Interactions

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 3 years ago

Possible Interaction: Caffeine and Prazosin

supplement:

Caffeine

Research Papers that Mention the Interaction

The NA-induced potentiation of I CAF was antagonized by an a 1 adrenoceptor antagonist, prazosin.
Current eye research  •  2001  |  View Paper
The alpha 1-adrenoceptor antagonist, prazosin and the 5-HT receptor antagonist, metergoline significantly enhanced the hypothermic effects of caffeine , probably involving a combined effect with their intrinsic hypothermic actions.
European journal of pharmacology  •  1992  |  View Paper
The discriminative effects of … mg/kg of caffeine were blocked dose-dependently and completely … alpha adrenergic receptor blocking drugs (phentolamine, prazosin and yohimbine) and were blocked partially by propranolol and by drugs having behavioral depressant … (diazepam, pentobarbital and the adenosine analogs, R-(-)-N6-(2-phenylisopropyl)adenosine, cyclohexyladenosine, 2-chloroadenosine).
The Journal of pharmacology and experimental therapeutics  •  1986  |  View Paper