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Discover Supplement-Drug Interactions

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Last Updated: 3 years ago

Possible Interaction: Caffeine and Piperine

supplement:

Caffeine

Research Papers that Mention the Interaction

It was also shown that piperine can potentiate the effect of a low dose of caffeine and can reverse the effect of diazepam.
Piperine improved the effect of a low dose of caffeine (25 mg/kg intraperitoneally after a shock of 2 s duration) in a first assessment (295.17 s vs 149.17 s, P = 0.026) compared to a higher dose of caffeine.
Journal of experimental pharmacology  •  2010  |  View Paper