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Discover Supplement-Drug Interactions

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Last Updated: a month ago

Possible Interaction: Caffeine and Phosphocreatine



Research Papers that Mention the Interaction

The total exercise time was 17.9 ± 6.0% longer in the caffeine (1,225 ± … s) than in the placebo trial (1,049 ± 73 s, p = 0.016), and muscle phosphocreatine concentration and pH (p < 0.05) were significantly lower in the latter sets of exercise after caffeine ingestion.
Front. Nutr.  •  2018  |  View Paper
Caffeine significantly delayed muscle fatigue during contraction, and the combination of caffeine and contraction additively decreased ATP and phosphocreatine contents.
Physiological reports  •  2015  |  View Paper
Incubation with 3 mm of caffeine activated AMPKα2 and reduced PCr and glycogen concentrations.
Acta physiologica  •  2011  |  View Paper
The myocardial content of adenosine triphosphate (ATP), creatine phosphate , as well as creatine was slightly but insignificantly increased after caffeine consumption.
Journal of cardiovascular pharmacology  •  2000  |  View Paper