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Discover Supplement-Drug Interactions
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Last Updated: 4 years ago
supplement:
Caffeine
drug:
Phosphocreatine
Research Papers that Mention the Interaction
“The myocardial content of adenosine triphosphate (ATP), creatine phosphate , as well as creatine was slightly but insignificantly increased after caffeine consumption.”
Effects of prolonged caffeine consumption on cardiac contractile function in rats.“Results The total exercise time was 17.9 ± 6.0% longer in the caffeine (1,… ± 86 s) than in the placebo trial (1,049 ± 73 s, p = 0.016), and muscle phosphocreatine concentration and pH (p < 0.05) were significantly … in the latter sets of exercise after caffeine ingestion.”
Improved Exercise Tolerance with Caffeine Is Associated with Modulation of both Peripheral and Central Neural Processes in Human Participants“Caffeine significantly delayed muscle fatigue during contraction, and the combination of caffeine and contraction additively decreased ATP and phosphocreatine contents.”
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