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Discover Supplement-Drug Interactions

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Last Updated: 3 years ago

Possible Interaction: Caffeine and Phenethylamines

supplement:

Caffeine

supplement:

Phenethylamines

Research Papers that Mention the Interaction

Ephedrine produced a significant BPM dose response from 0.5 to 5.0 µM. Caffeine increased BPM only at a toxic level of 250 µM. Adding caffeine to PEA or higenamine but not ephedrine further increased BPM.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association  •  2015  |  View Paper
These data clearly indicate that certain "legal" stimulants mimic the amphetamine cue and suggest that caffeine may interact additively with phenylethylamines to produce the cue.
Life sciences  •  1985  |  View Paper