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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
Research Papers that Mention the Interaction
“These data suggest that caffeine inhibits A1Rs expressed on PVN oxytocin neurons to negatively regulate energy balance in DIO mice.”
“We also show that caffeine excites oxytocin expressing neurons, and blockade of the action of oxytocin significantly attenuates the effect of caffeine on energy balance.”
Caffeine inhibits hypothalamic A1R to excite oxytocin neuron and ameliorate dietary obesity in mice“3 Caffeine (0.1–10 mm) inhibited, in a concentration‐dependent manner, contractions induced by electrical stimulation, potassium‐rich (60 mm K+) solution, sodium‐free solution or oxytocin (22.5 nm).”
“4 In Ca2+‐free solution, various substances oxytocin , sodium orthovanadate and prostaglandin E2) evoked sustained contractions that were suppressed by caffeine (5–10 mm).”
Caffeine acting on pregnant rat myometrium: analysis of its relaxant action and its failure to release Ca2+ from intracellular stores“ Caffeine (5-30 mM) produced no contraction, but slightly reduced the resting tension and strongly inhibited the oxytocin response both in the presence and in the absence of Ca.”
“Uterine contractions induced by oxytocin are also prevented by the administration of epinephrine together with theophylline or caffeine respectively, in doses which were ineffective by themselves.”
“Abstract It was found that caffeine inhibited the contractile response to oxytocin in isolated rat uterus.”
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