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Discover Supplement-Drug Interactions

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Last Updated: 3 years ago

Possible Interaction: Caffeine and Oxcarbazepine



Research Papers that Mention the Interaction

Low doses of caffeine given systemically inhibit antinociception by several analgesics (acetaminophen, amitriptyline, oxcarbazepine , cizolirtine), probably reflecting block of a component of action involving adenosine A(1) receptors.
Handbook of experimental pharmacology  •  2011  |  View Paper
Caffeine (1000-1500 nmol/paw), a nonselective adenosine receptor antagonist, as well as 1,3-dipropyl-8-cyclopentylxanthine (DPCPX) (10-30 nmol/paw), a selective A1 receptor antagonist, coadministered with OXC , significantly depressed its anti-hyperalgesic effect.
Die Pharmazie  •  2006  |  View Paper