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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Caffeine
drug:
Novobiocin
Research Papers that Mention the Interaction
“ Caffeine also reversed the inhibition of replicon initiation caused by novobiocin , which is not a DNA-damaging agent.”
Effect of caffeine on DNA synthesis in irradiated and unirradiated mammalian cells.“Results showed that NRR time, measured at day 28, was significantly reduced (… < 0.05) after exposure to environmental concentrations of each pharmaceutical caffeine = 15 μg·L−1; carbamazepine = 1 μg·L−1; ibuprofen = 5 μg·L−1; and novobiocin = 0.1 μg·L−1) when compared with control organisms.”
Stability of lysosomal membrane in Carcinus maenas acts as a biomarker of exposure to pharmaceuticals“If cells are synchronized by hydroxyurea (0.25 mM) in the S-phase of mitotic cycle, the addition of caffeine kills all the S-phase cells, while gamma-irradiation or novobiocine treatment markedly decreases the sensibilizing effect of caffeine.”
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