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Possible Interaction: Caffeine and Novobiocin

supplement:

Caffeine

Research Papers that Mention the Interaction

Caffeine also reversed the inhibition of replicon initiation caused by novobiocin , which is not a DNA-damaging agent.
Journal of molecular biology  •  1980  |  View Paper
Results showed that NRR time, measured at day 28, was significantly reduced (… < 0.05) after exposure to environmental concentrations of each pharmaceutical caffeine = 15 μg·L−1; carbamazepine = 1 μg·L−1; ibuprofen = 5 μg·L−1; and novobiocin = 0.1 μg·L−1) when compared with control organisms.
Environmental Monitoring and Assessment  •  2012  |  View Paper
If cells are synchronized by hydroxyurea (0.25 mM) in the S-phase of mitotic cycle, the addition of caffeine kills all the S-phase cells, while gamma-irradiation or novobiocine treatment markedly decreases the sensibilizing effect of caffeine.
Tsitologiia  •  1984  |  View Paper