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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Caffeine
drug:
Nitroglycerin
Research Papers that Mention the Interaction
“In patients with moderate-to-severe CAF pain, NTG 0.4% ointment effectively reduced CAF pain compared with placebo.”
Nitroglycerin 0.4% ointment vs placebo in the treatment of pain resulting from chronic anal fissure: a randomized, double-blind, placebo-controlled study“Previous studies have reported that topical treatment of CAF with glyceryl trinitrate ( GTN) reduces pain and promotes healing, but optimal treatment duration is unknown.”
“RESULTS:The group initially treated with nitroglycerin showed a higher healing rate of CAF (13 of 25, 52%) as compared with the botulinum toxin group (6 of 25, 24%) after the first 2 wk of therapy (p < 0.05).”
“ Nitroglycerin decreased calcium in both the presence and absence of extracellular calcium and strongly and progressively decreased the extent of transient increases in calcium induced by repeated applications of caffeine in the absence of extracellular calcium.”
Cytosolic-free calcium transients in cultured vascular smooth muscle cells: microfluorometric measurements.
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