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Last Updated: 3 months ago

Possible Interaction: Caffeine and Niflumic Acid

supplement:

Caffeine

Research Papers that Mention the Interaction

The …/l NFA on the GABA-evoked inward current were also strongly inhibited by nitrendipine (NTDP; an L-type calcium …(2-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid tetrakis (a highly selective calcium chelating reagent), caffeine (a widely available Ca2+ consuming drug) … fluid, in a concentration-dependent manner.
Experimental and therapeutic medicine  •  2016  |  View Paper
Upon application of the niflumic acid under K+-free conditions, most of the current induced by caffeine was inhibited.
Life sciences  •  2001  |  View Paper
Caffeine (10 mM) induced currents that reversed at ECl and were blocked by niflumic acid (10 microM).
The Journal of physiology  •  1997  |  View Paper
However, at a concentration of 100 microM, niflumic acid significantly inhibited IBK(Ca)) evoked by caffeine (10 mM) but not by NS1619 (1-(2'-hydroxy-5'-trifluoromethylphenyl)-5-trifluoromethyl-2(3 H) benzimidazolone; 20 microM).
In freshly dispersed portal vein cells clamped at -60 mV in caesium (Cs+)-containing solutions, niflumic acid (1-100 microM) inhibited calcium (Ca2+)-activated chloride currents (IC1(Ca)) induced by caffeine (10 mM) and by noradrenaline (10 microM).
European journal of pharmacology  •  1996  |  View Paper