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Discover Supplement-Drug Interactions

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Last Updated: 3 years ago

Possible Interaction: Caffeine and Monoamine Oxidase Inhibitors

Research Papers that Mention the Interaction

First, caffeine was shown to interact in vitro with a number of neuroleptics to form flaky precipitates and thus possibly impair the efficacy of these agents.8,9 Second, caffeine clinically antagonizes barbiturates” and monoamine oxidase inhibitors (MAOI).”
Comprehensive psychiatry  •  1981  |  View Paper
Large or multiple doses of caffeine which by themselves produced little effect, resulted in marked hyperthermia and increased toxicity when given in combination with a monoamine oxidase inhibitor.
European journal of pharmacology  •  1970  |  View Paper