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Last Updated: 3 years ago

Possible Interaction: Caffeine and Lidocaine

supplement:

Caffeine

Research Papers that Mention the Interaction

Combined use of caffeine and diazepam or lidocaine at certain stages of the early postresuscitation period accelerates the recovery of the neurological status and improves the outcome of resuscitation.
Anesteziologiia i reanimatologiia  •  1989  |  View Paper
In contrast, lignocaine enhanced the contractile response to caffeine (0.54-10.8 mM) possibly by lowering the threshold and mainly by increasing the maximal response.
Pharmacological research communications  •  1984  |  View Paper
Lidocaine, in contrast to procaine and tetracaine, does not inhibit the caffeine-induced contracture at pH 7.20 nor the associated calcium influx and efflux; instead, lidocaine potentiates the initial phase of the caffeine contracture.
The Journal of pharmacology and experimental therapeutics  •  1967  |  View Paper