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Discover Supplement-Drug Interactions

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Last Updated: 2 months ago

Possible Interaction: Caffeine and Leucovorin

supplement:

Caffeine

Research Papers that Mention the Interaction

PURPOSE To determine whether biochemical modulation with LV leucovorin ) enhances the efficacy of CAF (cyclophosphamide, doxorubicin, and fluorouracil) against metastatic breast cancer.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology  •  2003  |  View Paper
Folin administered showed a significant antagonistic effect to caffeine induced hyperactivity and slightly prolonged hexobarbital induced sleeping time in mice.
Nihon yakurigaku zasshi. Folia pharmacologica Japonica  •  1976  |  View Paper