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Last Updated: 3 years ago

Possible Interaction: Caffeine and Isoflurane

supplement:

Caffeine

Research Papers that Mention the Interaction

Our previous studies showed that caffeine , when given near the end of an anesthesia session, accelerated emergence from isoflurane anesthesia , likely caused by caffeine’s ability to elevate intracellular cAMP levels and to block adenosine receptors.
PloS one  •  2020  |  View Paper
Caffeine markedly augments neurotoxicity of isoflurane in the fetal macaque brain and challenges the assumption that caffeine is safe for premature infants.
Scientific Reports  •  2018  |  View Paper
The modest uncoupling effects of isoflurane , described here for the first time, are also enhanced by caffeine.
The Journal of Membrane Biology  •  2005  |  View Paper