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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Caffeine
drug:
Idoxuridine
Research Papers that Mention the Interaction
“We found that caffeine enhanced IUdR-DNA incorporation and IUdR-mediated radiosensitization by partially inhibiting repair (removal) of IUdR in DNA.”
The interaction between two radiosensitizers: 5-iododeoxyuridine and caffeine.“Abstract The induction of alkaline … activity in HeLa cells by 5-iodo-2′-deoxyuridine (IUdR) or hydrocortisone was inhibited in a dose-dependent manner by the addition of the xanthine derivatives caffeine , theophylline or 3-isobutyl-1-methylxanthine to the culture medium during the 72 hr of the induction.”
“For induction by halogenated pyrimidines, a 24-hr incubation of AKR2B cells with caffeine after 5-iodo-2'-deoxyuridine treatment resulted in marked suppression of the expression of ecotropic virus.”
Effect of caffeine on induction of endogenous type C virus in mouse cells in vitro.
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