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Discover Supplement-Drug Interactions
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Last Updated: 2 years ago
Research Papers that Mention the Interaction
“Adding caffeine to 200 mg ibuprofen produced significantly more analgesic effect at 45 and 60 min than ibuprofen 200 mg alone.”
“Conclusions: Caffeine increased the analgesic effect of ibuprofen 200 mg, through an earlier onset of analgesic effect.”
Ibuprofen compared with ibuprofen plus caffeine after third molar surgery“Our objective was to determine whether similar enhancement of analgesia could be demonstrated when caffeine is combined with ibuprofen.”
“Research suggests that combining ibuprofen with caffeine can increase the analgesic efficacy.”
“Compared with analgesic medication alone, combinations of caffeine with analgesic medications, including acetaminophen, acetylsalicylic acid, and ibuprofen , showed significantly improved efficacy in the treatment of patients with TTH or migraine, with favorable tolerability in the vast majority of patients.”
“There is evidence that caffeine alone or in association with Acetaminophen, Ibuprofen , or Aspirin can increase their analgesic effects.”
“Both ibuprofen 200 mg + caffeine 100 mg and ibuprofen 100 mg + caffeine 100 mg produced significantly more participants than placebo who achieved at least 50% of maximum pain relief over six hours, and both doses significantly reduced remedication rates (moderate quality evidence).”
“This study presented by Derry and colleagues assessed the analgesic efficacy of a single dose of ibuprofen plus caffeine when compared to placebo for moderate to severe postoperative pain.”
“In a recent Cochrane review based on 19 … with a total of 7238 patients, caffeine enhanced the efficacy of paracetamol, ibuprofen or aspirin with a number needed to treat (NNT) of about 16, comparable to the effect of doubling the dose of the primary analgesic, reported by other authors.”
“In adults, caffeine has been shown to enhance the effectiveness of most analgesics, including ibuprofen.”
“The presence of lagoon dissolved matter was significantly correlated with a 20-110% increase in half-life for 6 PPCPs caffeine , estrone, gemfibrozil, ibuprofen , naproxen, triclocarban).”
Effects of reclaimed water matrix on fate of pharmaceuticals and personal care products in soil.
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