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Discover Supplement-Drug Interactions

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Last Updated: 4 months ago

Possible Interaction: Caffeine and Hydrocortisone



Research Papers that Mention the Interaction

However, these data suggest that caffeine lowers the threshold for exercise-induced beta-endorphin and cortisol release , which may contribute to the reported benefits of caffeine on exercise endurance.
The Journal of clinical endocrinology and metabolism  •  2000  |  View Paper
Caffeine potentiated stress-related increases in plasma epinephrine and cortisol stress , more than doubling the responses observed in the control condition.
Psychosomatic medicine  •  1990  |  View Paper
Compared to placebo, caffeine also produced significant increases of diastolic blood pressure and cortisol.
Biological Psychiatry  •  1990  |  View Paper
Caffeine CAF ) 10 mg/kg raised plasma cortisol and rendered the subjects slightly panicked.
International clinical psychopharmacology  •  1988  |  View Paper
1 Our unit recently reported that the single-dose oral administration of caffeine produces dose-related and statistically significant increases in the plasma cortisol level.
Archives of general psychiatry  •  1985  |  View Paper
Caffeine supplementation was associated with higher postexercise cortisol levels (665 ± 200 vs. 543 ± 169 nmol/L, p < .0001) and facilitated greater peak blood lactate accumulation (analysis of variance main effect, p < .05).
International journal of sport nutrition and exercise metabolism  •  2018  |  View Paper
Cortisol concentrations also increased with CAF + CHO intake compared with PLA; however, there was no significant effect of CAF + CHO supplementation on testosterone concentrations.
European Journal of Applied Physiology  •  2014  |  View Paper
CONCLUSION The results of this study indicate that high doses of caffeine increase the responses of testosterone and cortisol.
CONCLUSION The results of this study indicate that high doses of caffeine increase the responses of testosterone and cortisol.
The Journal of sports medicine and physical fitness  •  2012  |  View Paper
SP-B mRNA was synergistically induced also by administration of caffeine with hydrocortisone (87.9±39.0), prednisolone (154±66.8), and betamethasone (123±6.4).
PloS one  •  2012  |  View Paper
However, a significant intervention effect (P = 0.04) and a time x intervention interaction (P-interaction = 0.02) were found for serum cortisol; cortisol concentrations were significantly higher following the caffeinated coffee intervention, compared to control, at 60 min and thereafter.
The Journal of nutrition  •  2011  |  View Paper
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