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Last Updated: 3 years ago

Possible Interaction: Caffeine and Heroin

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supplement:

Caffeine

drug:

Heroin

Research Papers that Mention the Interaction

“The stimulant effect of caffeine , as an additive in diacetylmorphine preparations for study purposes, may interfere with the pharmacodynamic effects of diacetylmorphine.”

Population pharmacokinetics of caffeine and its metabolites theobromine, paraxanthine and theophylline after inhalation in combination with diacetylmorphine.

Basic & clinical pharmacology & toxicology • 2005 | View Paper

“In previous studies we have shown highly significant increases in chromosome damage and sister chromatid exchanges in heroin addicts, particularly when caffeine and metabolic inhibitors are added to the medium.”

Detection of opiate‐enhanced increases in DNA damage, HPRT mutants, and the mutation frequency in human HUT‐78 cells

Environmental and molecular mutagenesis • 1994 | View Paper

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