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Discover Supplement-Drug Interactions
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Last Updated: 5 years ago
supplement:
Caffeine
supplement:
Glutathione
Research Papers that Mention the Interaction
“ Caffeine synergistically reduced the level of the apoptosis inhibitor glutatione after irradiation or CPt treatment.”
Expression of apoptosis-related oncoproteins and modulation of apoptosis by caffeine in human leukemic cells“ Acute caffeine decreased SOD activity (p<0.01) and improved glutathione (p<0.01) and luminol levels (p<0.05).”
Protective effect of low dose caffeine on psychological stress and cognitive function“Neurochemical analyses revealed that caffeine supplementation increased glutathione (GSH) content per se and protected against the increase in the levels of thiobarbituric acid reactive substances (TBARS) and oxidized diclorofluoresceine diacetate (DCFH-DA).”
“ Caffeine increased SOD activity, catalase and glutathione tissue expression and sustains the cadmium's effect on catalase and GSP-Px activity.”
“We propose that an oxidized intermediate of caffeine en route to trimethylurate is reduced by glutathione to the ring-opened uracil derivative.”
“These results revealed that caffeine and pyrocatechol in coffee brew may be the key constituents responsible for preventing the reduction of lens GSH and AsA in HFD-fed animals.”
Coffee brew intake can prevent the reduction of lens glutathione and ascorbic acid levels in HFD-fed animals.“The treatment with caffeine also caused an increase of GSH concentration and a decrease of MDA and AOPP concentrations.”
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