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Discover Supplement-Drug Interactions

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Last Updated: 3 years ago

Possible Interaction: Caffeine and Epoprostenol

supplement:

Caffeine

Research Papers that Mention the Interaction

Sensitization to the actions of prostacyclin , however, was reversed if caffeine was added ex vivo.
The Journal of pharmacology and experimental therapeutics  •  1993  |  View Paper
Caffeine significantly (p < 0.05) increased the output of prostacyclin (PGI2) from the perfused rat mesenteric vascular bed.
The increased production of a vasodilator such as PGI2 from blood vessels following exposure to caffeine may explain why caffeine has a beneficial effect in angina.
Prostaglandins, leukotrienes, and essential fatty acids  •  1994  |  View Paper