Allen Institute for Artificial Intelligence
supp.ai logo
supp.ai

Discover Supplement-Drug Interactions

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 5 years ago

Possible Interaction: Caffeine and Epinephrine

supplement:

Caffeine

supplement:

Epinephrine

Research Papers that Mention the Interaction

“ CAF ingestion significantly increased serum caffeine concentration and plasma adrenaline concentration following exercise.”
“Therefore, although CAF ingestion was associated with an increase in adrenaline , this was not associated with an expected decrease in neutrophil function.”
International journal of sport nutrition and exercise metabolism  •  2006  |  View Paper
“ Caffeine ingestion is associated with increases in the concentration of plasma epinephrine and epinephrine is associated with alterations in immune cell trafficking and function following intensive exercise.”
“… epinephrine concentrations … in CAF compared with PLA at pre-exercise [0.28 (0.05) nmol l−1 versus 0.08 (0.03) nmol l−1, P<0.…)] and immediately post-exercise [1.02 (0.16) nmol l−1 versuss 0.60 (0.13) nmol l−1, P<0.01].”
European Journal of Applied Physiology  •  2004  |  View Paper
“ Caffeine also increased by 32% the levels of free epinephrine excreted during the workday and the evening.”
Psychosomatic medicine  •  2002  |  View Paper
“ Caffeine increased the epinephrine and norepinephrine response associated with exercise and also increased blood lactate, glucose, and glycerol levels.”
Medicine and science in sports and exercise  •  2002  |  View Paper
“ Caffeine ingestion also resulted in higher plasma epinephrine levels than placebo ingestion (P < 0.05).”
Diabetes  •  2001  |  View Paper
“…,caffeine ingestion was associated with a greater increase in plasma lactate (caffeine: +…/L; placebo, +0.1 +/- 0.2 mmol/L; P < 0.005), epinephrine (caffeine, +223 +/- 82 pg/mL; placebo, +56 +/- 26 pg/mL; P < 0.05), … +/- 3 mg/mL; placebo, +2 +/- 2 mg/mL; P < 0.001) levels.”
The Journal of clinical endocrinology and metabolism  •  2000  |  View Paper
“Plasma epinephrine concentration was significantly increased 60 min after Caf ingestion compared with P1; however, this treatment effect disappeared once exercise began.”
Journal of applied physiology  •  1998  |  View Paper
“ Caffeine (Caf) ingestion increases plasma epinephrine (Epi) and exercise endurance; these results are frequently transferred to coffee (Cof) consumption.”
Journal of applied physiology  •  1998  |  View Paper
“Postexercise urine concentrations of epinephrine and caffeine were significantly higher in CAF.”
The Journal of sports medicine and physical fitness  •  1997  |  View Paper
“The caffeine ingestion resulted in a significant increase in endurance (4.12 +/- 0.36 and 4.93 +/- 0.60 min for placebo and caffeine, respectively) and resulted in a significant increase in plasma epinephrine concentration throughout the protocol but not in norepinephrine concentration.”
Journal of applied physiology  •  1996  |  View Paper
Show More