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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Caffeine
drug:
Disulfiram
Research Papers that Mention the Interaction
“However, the clearance of caffeine decreased by ≥50% after disulfiram in three of the 11 recovering alcoholics.”
“In normal subjects the total body clearance of caffeine declined 30% (142 to 99 ml/min) at the maintenance dose of disulfiram , 250 mg/day, and 29% (161 to 114 ml/min) at the loading dose of 500 mg/day.”
Inhibition of elimination of caffeine by disulfiram in normal subjects and recovering alcoholics“In saponin-skinned fibers, the amount of Ca2+ taken up, estimated by using the amplitude of 10 mM of caffeine contracture , was increased by disulfiram (27 μM).”
Effects of disulfiram on excitation-contraction coupling in rat soleus muscle
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