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Last Updated: 3 years ago

Possible Interaction: Caffeine and Dipyridamole

supplement:

Caffeine

Research Papers that Mention the Interaction

Patients scheduled for (201)Tl myocardial perfusion using pharmacologic stress with dipyridamole or adenosine are advised to abstain from caffeine for 24 h before the test.
Journal of nuclear medicine technology  •  2002  |  View Paper
Because of the widespread use of caffeine , this pharmacologic interaction may be of clinical importance, for example, in the diagnostic use of dipyridamole in thallium‐201 myocardial imaging.
Caffeine induced … dipyridamole , with a significant negative correlation between the dose of caffeine on the one hand (0, 1, 2, and 4 mg/kg) and the … = −0.53), pulse pressure (r = −0.50), heart rate (r = −0.95), and rate‐pressure product (r = −0.93) on the other hand.
We conclude that caffeine attenuates the hemodynamic response to dipyridamole infusion in humans in a dose‐dependent fashion.
Clinical pharmacology and therapeutics  •  1991  |  View Paper
Background: It is commonly thought that caffeine and theophylline interfere with adenosine and dipyridamole induced coronary hyperemia, thus frequently delaying scheduled assessments after inadvertent consumption.
The interactions of theophylline with adenosine‐hyperemia are less clear while both caffeine and theophylline show significant interaction with dipyridamole‐hyperemia.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions  •  2009  |  View Paper
The available data indicate a significant influence of recent caffeine intake on cardiac perfusion measurements during adenosine and dipyridamole induced hyperemia.
Nutrients  •  2018  |  View Paper
The coronary vasodilatory effect of dipyridamole is competitively blocked by caffeine.
The American journal of cardiology  •  2010  |  View Paper
Rosuvastatin treatment significantly increased the vasodilator response to dipyridamole , which was prevented by caffeine.
Arteriosclerosis, thrombosis, and vascular biology  •  2009  |  View Paper
Although caffeine attenuates the vasodilatation produced by dipyridamole and adenosine, and is therefore contraindicated when these agents are used for myocardial perfusion scintigraphy, caffeine levels in clinical patients undergoing standard imaging protocols have not been studied.
European Journal of Nuclear Medicine  •  2004  |  View Paper
Furthermore, CSC and caffeine actions , inhibiting MPO as well as LDH releases, would contribute to their possible benefit in the treatment of neurodegenerative diseases, including DP.
Neurochemistry International  •  2010  |  View Paper
The effects of dilazep, papaverine and EHNA, but not of dipyridamole , were antagonized by caffeine.
Pharmacology Biochemistry and Behavior  •  1986  |  View Paper
3 Dipyridamole 10 μm potentiated the inhibitory effect of adenosine 30 μm on ACh release and antagonized both the stimulatory and inhibitory effects of caffeine on ACh release.
British journal of pharmacology  •  1984  |  View Paper
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