Allen Institute for Artificial Intelligence
supp.ai logo
supp.ai

Discover Supplement-Drug Interactions

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 2 years ago

Possible Interaction: Caffeine and Dinoprost

supplement:

Caffeine

Research Papers that Mention the Interaction

In contrast to its stimulatory effect on PGF2 alpha output from the guinea-pig uterus superfused in vitro and guinea-pig endometrium in culture, caffeine inhibited the output of PGF2 alpha from guinea-pig glandular epithelial cells in culture.
Prostaglandins, leukotrienes, and essential fatty acids  •  1997  |  View Paper
5 These studies suggest that caffeine stimulates uterine PGF2α synthesis and release by a mechanism dependent upon intracellular calcium, but this mechanism is not mediated by activation of any of the three well‐characterized ryanodine receptors or by calmodulin.
British journal of pharmacology  •  1994  |  View Paper
The outputs of PGE2 and PGF2 alpha were also increased by caffeine.
Prostaglandins, leukotrienes, and essential fatty acids  •  1994  |  View Paper
In potassium depolarized muscle, PGF2 alpha abolished the contractile response to caffeine , indicating an action at the trigger calcium site.
Archives internationales de pharmacodynamie et de therapie  •  1980  |  View Paper
Caffeine and procaine suppressed the increase in ionic conductance and depolarization produced by noradrenaline or prostaglandin F2alpha.
The Japanese journal of physiology  •  1977  |  View Paper