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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
Research Papers that Mention the Interaction
“In contrast to its stimulatory effect on PGF2 alpha output from the guinea-pig uterus superfused in vitro and guinea-pig endometrium in culture, caffeine inhibited the output of PGF2 alpha from guinea-pig glandular epithelial cells in culture.”
“5 These studies suggest that caffeine stimulates uterine PGF2α synthesis and release by a mechanism dependent upon intracellular calcium, but this mechanism is not mediated by activation of any of the three well‐characterized ryanodine receptors or by calmodulin.”
“The outputs of PGE2 and PGF2 alpha were also increased by caffeine.”
The effect of caffeine on prostaglandin output from the perfused mesenteric vascular bed of the rat.“In potassium depolarized muscle, PGF2 alpha abolished the contractile response to caffeine , indicating an action at the trigger calcium site.”
“ Caffeine and procaine suppressed the increase in ionic conductance and depolarization produced by noradrenaline or prostaglandin F2alpha.”
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