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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Caffeine
supplement:
Dextroamphetamine
Research Papers that Mention the Interaction
“Additionally, although caffeine shares stimulus functions with d-amphetamine , it does so under limited conditions and should be considered to have a relatively lower dependence potential.”
Stimulus functions of caffeine in humans: Relation to dependence potential“ Caffeine and d-amphetamine dose dependently increased locomotor activity.”
D1 and D2 dopamine receptor antagonists block caffeine-induced stimulation of locomotor activity in rats“Enhancement of d-amphetamine activity occurred with simultaneous and 30 min caffeine pretreatment.”
“Intraperitoneal injection of water or d-amphetamine exacerbates this effect, while caffeine has a modest antagonistic effect.”
“The combination of caffeine and d-amphetamine is synergistic and leads to a rapid loss in body temperature with death occurring in less than 3 hours.”
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