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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Caffeine
drug:
Daunorubicin
Research Papers that Mention the Interaction
“ Caffeine , which is an inhibitor of ataxia telangiectasia mutated protein (ATM) and ataxia telangiectasia mutated and Rad3-related protein (ATR), and the Chk1 inhibitor inhibited the TER increases induced by daunorubicin and rebeccamycin, whereas a Chk2 inhibitor did not.”
Checkpoint Kinase 1 Activation Enhances Intestinal Epithelial Barrier Function via Regulation of Claudin-5 Expression“The degree of cooperativity for daunorubicin activation of Ca2+ release from SR also increases in the presence of caffeine.”
Mechanism of anthraquinone-induced calcium release from skeletal muscle sarcoplasmic reticulum.“It is found that the complexation of DAU with DNA in the presence of CAF is mainly affected by the CAF–DNA complexation, whereas the binding of either DOX or NOG to DNA is affected approximately equally by both the CAF–DNA complexation and CAF-antibiotic hetero-association.”
Complexation of anthracycline drugs with DNA in the presence of caffeine“In this work, we demonstrate that caffeine and other methylxanthines--pentoxifylline and theophylline--significantly decrease mutagenicity of the anticancer aromatic drugs daunomycin , doxorubicin and mitoxantrone.”
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