Allen Institute for Artificial Intelligence logo

Discover Supplement-Drug Interactions

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 2 months ago

Possible Interaction: Caffeine and Creatinine



Research Papers that Mention the Interaction

Total urine output of water, calcium, magnesium, sodium, chloride, potassium and creatinine increased in the two hours following caffeine ingestion when compared to the control beverage.
Life sciences  •  1990  |  View Paper
Urine flow rate (+63 +/- 57%), water output/input ratio (+49 +/- 54%) and creatinine clearance (+79 +/- 102%) increased significantly after the administration of caffeine.
Biology of the neonate  •  1990  |  View Paper
Moreover, caffeine significantly decreased creatinine clearance after 4 and 8 weeks (CrCl, Cont:3.5 ± 0.4, Caff: 2.2 ± 0.2 L/kg/day, p<0.05) and increased protein/CrCl ratio (Cont:323 ± 30, Caff: 527 ± 33 mg/L/day).
Renal failure  •  2001  |  View Paper
In addition, caffeine potentiated the transient reduction in creatinine clearance (CrCl) induced by PAN.
Renal failure  •  2000  |  View Paper
Although baseline serum creatinine did not … by caffeine exposure, patients receiving caffeine had … peak creatinine (median 1.0 mg/dl vs. 1.5 mg/dl; p = 0.008) and absolute creatinine change (… 0.42 mg/dl vs. 0.68 mg/dl; p = 0.003) than those who did not.
Pediatric Nephrology  •  2018  |  View Paper